Anomalous Emotion Regulation & Reward Network Connectivity Underlying Suicidal & Non-Suicidal Self-Injury in Early Psychosis

The study focuses on early psychosis (EP), where suicide is the leading cause of death within five years of diagnosis. It compares effective connectivity in emotion regulation and reward network regions among participants with lifetime non-suicidal self-injury (NSSI) or suicide attempts, with and without EP. Using resting-state functional connectivity analysis, the research seeks to identify network-level alterations that may differentiate self-injury phenotypes. Findings could inform targeted interventions for suicide prevention in early psychosis, a group often excluded from self-injury studies.